دانلود کتاب Free radicals and oxidation phenomena in biological systems

This concise reference offers an incomparable analysis of the biological processes mediated by free radicals from a toxicological point of view - explaining in detail the chemistry and biochemistry of all principal types of radicals and providing easy access to information in an integrated, coherent presentation.Investigating the multiple forms in which radicals participate in living organisms, Free Radicals and Oxidation Phenomena in Biological Systems discusses organic radicals in the metabolism of xenobiotics and endogenous organic radicals as intermediates in cellular metabolism ... explores biomolecular targets for radicals, including proteins, nucleic acids, and unsaturated fatty acyl moieties in lipids ... describes the excessive activation of phagocytes and the irradiation and metabolic activation of chemicals in the pathology of radicals ... examines the mechanism of action and potential clinical applications of antioxidants ... supplies strategies to avoid deleterious effects of mediated free radicals ... and much more.With over 700 bibliographic citations and illustrations, Free Radicals and Oxidation Phenomena in Biological Systems is an excellent reference for biochemists, pharmacologists, pharmaceutical researchers, food scientists and technologists, nutritionists, toxicologists, chemists, biologists, and graduate students in these disciplines.  Read more... Ch. I. Definitions, Properties, and Reactions of Radicals. I.1. Definitions and Properties. I.2. Reactions of Radicals. I.3. Properties and Reactions of Radicals: An Overview Emphasizing Biologically Relevant Information --Ch. II. Biologically Relevant Radicals. II.1. Organic Radicals as Catalytic Intermediates and/or Products of the Metabolism of Xenobiotics. II.2. Endogenous Organic Radicals as Intermediates in Cellular Metabolism. II.3. Biologically Relevant Inorganic Radicals and Related Reactive Molecular Species --Ch. III. Biomolecular Targets for Radicals and Reactive Oxygen Species. III.1. Small Organic Biomolecules. III.2. Unsaturated Fatty Acyl Moieties in Lipids. III.3. Proteins. III.4. Nucleic Acids. III.5. Radical and Reactive Oxygen Species-Mediated Bioorganic Reactions: A Synthetic Discussion --Ch. IV. Pathology of Radicals and Reactive Oxygen Species. IV.1. Radicals and Reactive Oxygen Species: Necessary But Dangerous for Aerobic Life.