دانلود کتاب Carbohydrate Recognition: Biological Problems, Methods, and Applications

This book contains contributions from interdisciplinary scientists to collectively address the issue of targeting carbohydrate recognition for the development of novel therapeutic and diagnostic agents. The book covers (1) biological problems involving carbohydrate recognition, (2) structural factors mediating carbohydrate recognition, (3) design and synthesis of lectin mimics that recognize carbohydrate ligands with high specificity and affinity, and (4) modulation of biological and pathological processes through carbohydrate recognition.Content: Chapter 1 Mammalian Glycan Biosynthesis: Building a Template for Biological Recognition (pages 1–32): M. Adam Meledeo, Venkata D. P. Paruchuri, Jian Du, Zhiyun Wang and Kevin J. YaremaChapter 2 The Roles of Carbohydrate Binding in Cell Adhesion and Inflammation (pages 33–63): Ken Kitajima and Chihiro SatoChapter 3 The Role of Carbohydrates in Viral Infections (pages 65–91): Gillian M. AirChapter 4 The Role of Carbohydrates in Bacterial Infections (pages 93–106): Roland J. PietersChapter 5 The Roles of Carbohydrate Binding in Fertilization (pages 107–132): David J. MillerChapter 6 Carbohydrate Biomarkers (pages 133–156): Yunfeng Cheng, Nanting Ni, Hanjing Peng, Shan Jin and Binghe WangChapter 7 Galectins and their Role in Various Biological Processes (pages 157–180): Sarika Saraswati, Ashley Stanley Block and Alan B. DiekmanChapter 8 Glycoimmunology (pages 181–203): Ani Grigorian, Barbara Newton and Michael DemetriouChapter 9 Tools for Glycomics: Glycan and Lectin Microarrays (pages 205–227): Christopher Campbell and Jeff GildersleeveChapter 10 Combinatorial Biosynthesis of Complex Carbohydrates (pages 229–255): Hai Yu and Xi ChenChapter 11 Mass Spectrometry in Carbohydrate Sequencing and Binding Analysis (pages 257–300): Gregory O. Staples and Joseph ZaiaChapter 12 Synthetic Lectin Mimics Artificial Carbohydrate Receptors (pages 301–327): Xiaochuan Yang, Yunfeng Cheng and Binghe WangChapter 13 Lectin Binding and its Structural Basis (pages 329–347): Annabelle Varrot, Bertrand Blanchard and Anne ImbertyChapter 14 Multivalency in Carbohydrate Binding (pages 349–370): Mark L. Wolfenden and Mary J. CloningerChapter 15 Carbohydrate Binding Agents: Potential Therapeutics with Multiple Inhibitory Actions against Enveloped Viruses (pages 371–407): K. O. Francois and J. BalzariniChapter 16 Informatics for Glycobiology and Glycomics (pages 409–426): Kiyoko F. Aoki?Kinoshita