دانلود کتاب Ligand Design for G Protein-coupled Receptors (Methods and Principles in Medicinal Chemistry)

Content: G protein-coupled receptors in the human genome / Robert Fredriksson and Helgi B. Schiöth -- Why G protein-coupled receptors databases are needed / Jacques Haiech ... [et al.] -- A novel drug screening assay for G protein-coupled receptors / Brian F. O'Dowd ... [et al.] -- Importance of GPCR dimerization for function : the case of the class C GPCRs / Laurent Prézeau ... [et al.] -- Molecular mechanisms of GPCR activation / Robert P. Bywater and Paul Denny-Gouldson -- Allosteric properties and regulation of G protein-coupled receptors / Jean-Luc Galzi ... [et al.] -- Chemogenomics approaches to ligand design / Thomas Klabunde -- Strategies for the design of pGPCR-targeted libraries / Nikolay P. Savchuk, Sergey E. Tkachenko, and Konstantin V. Balakin -- Ligand-based rational design : virtual screening / David E. Clark and Christopher Higgs -- 3-D structure of G protein-coupled receptors / Leonardo Pardo ... [et al.] -- 7TM models in structure-based drug design / Frank E. Blaney, Anna-Maria Capelli, and Giovanna Tedesco -- Receptor-based rational design : virtual screening / Didier Rognan