دانلود کتاب DNA Repair in Cancer Therapy (Cancer Drug Discovery and Development)

Name: DNA Repair in Cancer Therapy (Cancer Drug Discovery and Development)
Availability: InStock
Author: Lawrence C. Panasci
ISBN: 1588292983, 1592597351

by Lawrence C. Panasci

عنوان فارسی: تعمیر DNA در درمان سرطان ( سرطان با مواد مخدر کشف و توسعه )
ناشر: Humana Press
سال: 2004
ویرایش: 1
زبان: انگلیسی
تعداد صفحه (نسخه چاپی - نسخه الکترونیکی): 362-376
شابک: 1588292983, 1592597351
نوع فایل: PDF دانلود نرم افزار مطالعه
حجم: 6.00 مگابایت

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جزییات کتاب

A comprehensive review of the recent developments in DNA repair that have potential for translational and clinical applications. The authors explain in detail the various mechanisms by which cancer cells can circumvent anticancer therapy and limits its usefulness in patients. They also review the clinical impact of such novel inhibitors of DNA repair mechanisms as methylguanine-DNA-methyltransferase. Also examined are inhibitors of other DNA repair enzymes such as PARP and DNA-PK, now under development and close to clinical trials. The book captures-for both cancer researchers and practicing oncologists dealing with hallmark "relapse" or "drug resistance" phenomena on a daily basis-the many exciting new uses of DNA repair inhibitors, either alone or in combination with anticancer therapies.

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