دانلود کتاب Computer Techniques in Preclinical and Clinical Drug Development

It is estimated that 80 to 90 per cent of drugs under development never make it to the marketplace due to insufficient clinical activity, unacceptable toxicity, rapid appearance of drug resistance, or other factors that should be, at least partially, predictable from preclinical testing. This new text asks the question, ''How can we use computational methods to improve the success rate in drug development?'' Computer Techniques in Preclinical and Clinical Drug Development shows how modeling makes it possible to extract the maximum amount of information and predictive value from preclinical dat. Read more... Abstract: It is estimated that 80 to 90 per cent of drugs under development never make it to the marketplace due to insufficient clinical activity, unacceptable toxicity, rapid appearance of drug resistance, or other factors that should be, at least partially, predictable from preclinical testing. This new text asks the question, ''How can we use computational methods to improve the success rate in drug development?'' Computer Techniques in Preclinical and Clinical Drug Development shows how modeling makes it possible to extract the maximum amount of information and predictive value from preclinical dat