جزییات کتاب
Genomics is a new discipline that is revolutionizing the way biological and medical research is done. The human genome is almost completely sequenced, which will help to accelerate research and development in Genomics even more. The chapters in this book try to capture the rapidly evolving field. Overviews of nucleic acid technologies, proteomics and bioinformatics are followed by chapters on applications, including human health, agriculture and comparative genomics. The book also includes two chapters on legal and ethical issues of Genomics, a topic that is becoming more and more important. Content: Chapter 1 Genome Projects of Model Organisms (pages 4–39): Alfred Puhler, Doris Jording, Jorn Kalinowski, Detlev Buttgereit, Renate Renkawitz?Pohl, Lothar Altschmied, Antoin E. Danchin, Horst Feldmann, Hans?Peter Klenk and Manfred KrogerChapter 2 The Human Genome Project (pages 41–59): Lap Chee Tsui and Steve, W. SchererChapter 3 Genetic Disease (pages 61–104): Graham DellaireChapter 4 Genomics and Human Disease (pages 105–122): Roger C. GreenChapter 5 Pharmaceutical Bioinformatics and Drug Discovery (pages 123–144): Chandra S. Ramanathan and Daniel B. DavisonChapter 6 Agri?Food and Genomics (pages 145–164): Isobel A. P. Parkin, Stephen J. Robinson, Andrew G. Sharpe, Kevin Rozwadowski, Dwayne Hegedus and Derek J. LydiateChapter 7 Genomic Mapping and Positional Cloning, with Emphasis on Plant Science (pages 165–182): Apichart Vanavichit, Somvong Tragoonrung and Theerayut ToojindaChapter 8 Sequencing Technology (pages 193–226): Lyle R. Middendorf, Patrick G. Humphrey, Narasimhachari Narayanan and Stephen C. RoemerChapter 9 A DNA Microarrays Fabrication Strategy for Research Laboratories (pages 227–240): Daniel C. Tessier, David Y. Thomas and Roland BrousseauChapter 10 Two?Dimensional Gel Electrophoresis and Mass Spectrometry for Proteomic Studies: State?of?the?Art (pages 241–268): Daniel FigeysChapter 11 Proteome Analysis by Capillary Electrophoresis (pages 269–280): Norman J. Dovichi, Shen Hu, David Michels, Zheru Zhang and Sergey N. KrylovChapter 12 Using the Molecular Biology Data (pages 281–300): Evgeni M. Zdobnov, Rodrigo Lopez, Rolf Apweiler and Thure EtzoldChapter 13 Tools for DNA Technologies (pages 301–324): Peter RiceChapter 14 Tools for Protein Technologies (pages 325–344): David S. WishartChapter 15 Structure Information (pages 345–360): Miroslaw Cygler, Allan Matte and Joseph D. SchragChapter 16 Automated Genome Annotation and Comparative Genomics (pages 361–378): Shuba Gopal and Terry GaasterlandChapter 17 Genomic Data Representation through Images?Magpie as an Example (pages 379–397): Paul Gordon, Terry Gaasterland and Christoph W. SensenChapter 18 Interaction Databases (pages 399–413): Gary D. Bader and Christopher W. V. HogueChapter 19 Ethical Aspects of Genome Research and Banking (pages 416–429): Bartha Maria KnoppersChapter 20 Genomics?Five Years from Now (pages 431–439): Christoph W. Sensen