جزییات کتاب
Unresolved structure-activity relationships in anthracycline analogue development / Edward M. Acton --Non-cross-resistant anthracyclines with reduced basicity and increased stability of the glycosidic bond / Waldemar Priebe, Piotr Skibicki, Oscar Varela, Nouri Neamati, Marcos Sznaidman, Krzysztof Dziewiszek, Grzegorz Grynkiewicz, Derek Horton, Yiyu Zou, Yi-He Ling, and Roman Perez-Soler --Fluorinated anthracyclinones and their glycosylated products / Antonio Guidi, Franca Canfarini, Alessandro Giolitti, Franco Pasqui, Vittorio Pestellini, and Federico Arcamone --Semisynthetic rhodomycins and anthracycline prodrugs / Cenek Kolar, Klaus Bosslet, Jörg Czech, Manfred Gerken, Peter Hermentin, Dieter Hoffmann, and Hans-Harold Sedlacek --Synthetic options for reversal of anthracycline resistance and cardiotoxicity / Claude Monneret, Jean-Claude Florent, Jean-Pierre Gesson, Jean-Claude Jacquesy, François Tillequin, and Michel Koch --Synthesis and biological activities of fluorinated daunorubicin and doxorubicin analogues / Tsutomu Tsuchiya and Yasushi Takagi --Redox chemistry of anthracyclines and use of oxomorpholinyl radicals / Tad H. Koch and Giorgio Gaudiano --Synthesis of anthraquinone analogues of linked anthracycline / Ping Ge and Richard A. Russell --Synthesis and study of structure-activity relationships of new classes of anthracyclines / Antonino Suarato, Francesco Angelucci, Alberto Bargiotti, Michele Caruso, Daniela Faiardi, Laura Capolongo, Cristina Geroni, Marina Ripamonti, and Maria Grandi --Molecular recognition of DNA by daunorubicin / Jonathan B. Chaires --Adducts of DNA and anthracycline antibiotics : structures, interactions, and activities / Jasmine Y.-T. Wang, Mark Chao, and Andrew H.-J. Wang --DNA topoisomerases and their inhibition by anthracyclines / Yves Pommier --Anthracycline antihelicase action : new mechanism with implications for guanosine-cytidine intercalation specificity / Nicholas R. Bachur, Robin Johnson, Fang Yu, Robert Hickey, and Linda Malkas --Membrane biophysical parameters influencing anthracycline action / Ratna Mehta and Thomas G. Burke --Signal transduction systems in doxorubicin hydrochloride mechanism of action / Paul Vichi, James Song, Jean Hess, and Thomas R. Tritton --Analysis of multidrug transporter in living cells : application to uptake and release of anthracycline derivatives by drug-resistant K562 cells / Arlette Garnier-Suillerot, Frédéric Frézard, Marie-Nicole Borrel, Elene Pereira, Jolanta Tarasiuk, and Marina Fiallo --Role of reactive-oxygen metabolism in cardiac toxicity of anthracycline antibiotics / James H. Doroshow --Amelioration of anthracycline-induced cardiotoxicity by organic chemicals / Donald T. Witiak and Eugene H. Herman --Use of drug carriers to ameliorate the therapeutic index of anthracycline antibiotics / Roman Perez-Soler, Steven Sugarman, Yiyu Zou, and Waldemar Priebe