جزییات کتاب
This book offers an important reference source about the most common classes of pesticides for researchers engaged in the area of neurotoxicology, metabolism, and epidemiology. The book presents details about thorough characterization of target and non-target enzymes and proteins involved in toxicity and metabolism; and epidemiology of poisonings and fatalities in people from short- and long- term exposures to these pesticides in different occupational settings on an individual country basis as well as on a global basis. The early portion of the book deals with metabolism, mechanisms and biomonitoring of anticholinesterase pesticides, while the later part deals with epidemiological studies, regulatory issues, and therapeutic intervention.Content: Chapter 1 Acetylcholinesterase and Acetylcholine Receptors: Brain Regional Heterogeneity (pages 1–18): Haruo Kobayashi, Tadahiko Suzuki, Fumiaki Akahori and Tetsuo SatohChapter 2 Genomic Implications of Anticholinesterase Sensitivities (pages 19–24): Jonathan E. Cohen, Alon Friedman, Gabrial Zimmermann and Hermona SoreqChapter 3 Butyrylcholinesterase: Overview, Structure, and Function (pages 25–41): Oksana Lockridge, Ellen G. Duysen and Patrick MassonChapter 4 Carboxylesterases: Overview, Structure, Function, and Polymorphism (pages 43–56): Masakiyo Hosokawa and Tetsuo SatohChapter 5 Carboxylesterases in the Metabolism and Toxicity of Pesticides (pages 57–75): Colin J. Jackson, John G. Oakeshott, Juan C. Sanchez?Hernandez and Craig E. WheelockChapter 6 The Metabolic Activation and Detoxication of Anticholinesterase Insecticides (pages 77–84): Janice E. Chambers, Edward C. Meek and Matthew RossChapter 7 Paraoxonase 1: Structure, Function, and Polymorphisms (pages 85–95): Lucio G. Costa and Clement E. FurlongChapter 8 Long?Term Neurotoxicological Effects of Anticholinesterases after either Acute or Chronic Exposure (pages 97–108): Angelo Moretto, Manuela Tiramani and Claudio ColosioChapter 9 Molecular Toxicology of Neuropathy Target Esterase (pages 109–120): Yi?Jun Wu and Ping?An ChangChapter 10 Detoxication of Anticholinesterase Pesticides (pages 121–132): Miguel A. Sogorb and Eugenio VilanovaChapter 11 Involvement of Oxidative Stress in Anticholinesterase Pesticide Toxicity (pages 133–147): Dejan Milatovic, Michael Aschner, Ramesh C. Gupta, Snjezana Zaja?Milatovic and Gregory BarnesChapter 12 Central Mechanisms of Seizures and Lethality Following Anticholinesterase Pesticide Exposure (pages 149–164): Andrzej Dekundy and Rafal M. KaminskiChapter 13 Apoptosis Induced by Anticholinesterase Pesticides (pages 165–174): Qing LiChapter 14 Gene Expression (pages 175–188): Shirin Pournourmohammadi and Mohammad AbdollahiChapter 15 Organophosphates as Endocrine Disruptors (pages 189–202): Shigeyuki Kitamura, Kazumi Sugihara, Nariaki Fujimoto and Takeshi YamazakiChapter 16 Developmental Neurotoxicity of Anticholinesterase Pesticides (pages 203–223): John Flaskos and Magdalini SachanaChapter 17 Toxicity of Anticholinesterase Pesticides in Neonates and Children (pages 225–236): Diane Rohlman and Linda McCauleyChapter 18 Neurotoxicity of Organophosphates and Carbamates (pages 237–265): Kiran Dip Gill, Govinder Flora, Vidhu Pachauri and Swaran J. S. FloraChapter 19 Biomonitoring of Pesticides: Pharmacokinetics of Organophosphorus and Carbamate Insecticides (pages 267–287): Charles TimchalkChapter 20 Novel Biomarkers of Organophosphate Exposure (pages 289–302): Tetsuo Satoh, Salmaan H. Inayat?Hussain, Michihiro Kamijima and Jun UeyamaChapter 21 Biomarkers of Carcinogenesis in Relation to Pesticide Poisoning (pages 303–313): Manashi Bagchi, Shirley Zafra?Stone, Francis C. Lau and Debasis BagchiChapter 22 Anticholinesterase Pesticides Interactions (pages 315–327): Ramesh C. Gupta and Dejan MilatovicChapter 23 Interaction of Anticholinesterase Pesticides with Metals (pages 329–339): Jitendra K. Malik, Avinash G. Telang, Ashok Kumar and Ramesh C. GuptaChapter 24 Epidemiological Studies of Anticholinesterase Pesticide Poisoning: Global Impact (pages 341–355): Claudio Colosio, Francesca Vellere and Angelo MorettoChapter 25 Epidemiological Studies of Anticholinesterase Pesticide Poisoning in Chile (pages 357–363): Floria Pancetti, Muriel Ramirez and Mauricio CastilloChapter 26 Epidemiological Studies of Anticholinesterase Pesticide Poisoning in China (pages 365–377): Yueming JiangChapter 27 Epidemiological Studies of Anticholinesterase Pesticide Poisoning in Egypt (pages 379–401): Sameeh A. MansourChapter 28 Epidemiological Studies of Anticholinesterase Pesticide Poisoning in Greece (pages 403–416): M. Stefanidou, S. Athanaselis, C. Spiliopoulou and C. MaraveliasChapter 29 Epidemiological Studies of Anticholinesterase Pesticide Poisoning in India (pages 417–431): P. K. GuptaChapter 30 Poisoning with Anticholinesterase Insecticides in Iran (pages 433–446): Mohammad AbdollahiChapter 31 Epidemiological Studies of Anticholinesterase Pesticide Poisoning in Israel (pages 447–456): Yoram Finkelstein, Elihu D. Richiter and Michael AschnerChapter 32 Epidemiological Studies of Anticholinesterase Pesticide Poisoning in Japan (pages 457–462): Takemi Yoshida and Yumiko KurokiChapter 33 Epidemiological Studies of Anticholinesterase Pesticide Poisoning in Korea (pages 463–470): Hyung?Keun Roh, Bum Jin Oh, Mi?Jin Lee and Joo?Hyun SuhChapter 34 Epidemiological Studies of Anticholinesterase Pesticide Poisoning in Mexico (pages 471–480): Betzabet Quintanilla?Vega, Norma Perez?Herrera and Elizabeth Rojas?GarciaChapter 35 Epidemiological Studies of Anticholinesterase Pesticide Poisoning in Serbia (pages 481–494): Milan Jokanovic, Biljana Antonijevic and Slavica VuccinicChapter 36 Epidemiological Studies of Anticholinesterase Pesticide Poisoning in Spain (pages 495–508): Antonio F. Hernandez, Tesifon Parron, Jose L. Serrano and Porfirio MarinChapter 37 Epidemiological Studies of Anticholinesterase Pesticide Poisoning in Taiwan (pages 509–521): Tzeng Jih Lin, Dong Zong Hung, Jin Lian Tsai, Sheng Chuan Hu and Jou?Fang DengChapter 38 Epidemiological Studies of Anticholinesterase Pesticide Poisoning in Thailand (pages 523–532): Winai WananukulChapter 39 Epidemiological Studies of Anticholinesterase Pesticide Poisoning in Turkey (pages 533–540): Ismet CokChapter 40 Epidemiology of Anticholinesterase Pesticide Poisoning in the United States (pages 541–566): Anna M. FanChapter 41 Regulatory Aspects of Anticholinesterase Pesticides (pages 567–579): Kai SavolainenChapter 42 Medical Treatment of Poisoning with Organophosphates and Carbamates (pages 581–597): Milan Jokanovic