دانلود کتاب Chemical Synthetic Biology

Chemistry plays a very important role in the emerging field of synthetic biology. In particular, chemical synthetic biology is concerned with the synthesis of chemical structures, such as proteins, that do not exist in nature. With contributions from leading international experts, Chemical Synthetic Biology shows how chemistry underpins synthetic biology. The book is an essential guide to this fascinating new field, and will find a place on the bookshelves of researchers and students working in synthetic chemistry, synthetic and molecular biology, bioengineering, systems biology, computational genomics, and bioinformatics.Content: Chapter 1 Searching for Nucleic Acid Alternatives (pages 5–45): Albert EschenmoserChapter 2 Never?Born RNAs: Versatile Modules for Chemical Synthetic Biology (pages 47–67): Davide De Lucrezia, Fabrizio Anella, Cristiano Chiarabelli and Pier Luigi LuisiChapter 3 Synthetic Biology, Tinkering Biology, and Artificial Biology: A Perspective from Chemistry (pages 69–106): Steven A. Benner, Fei Chen and Zunyi YangChapter 4 Peptide Nucleic Acids (PNAs) as a Tool in Chemical Biology (pages 107–118): Peter E. NielsenChapter 5 High Solubility of Random?Sequence Proteins Consisting of Five Kinds of Primitive Amino Acids (pages 119–137): Nobuhide Doi, Koichi Kakukawa, Yuko Oishi and Hiroshi YanagawaChapter 6 Experimental Approach for Early Evolution of Protein Function (pages 139–153): Hitoshi Toyota, Yuuki Hayashi, Asao Yamauchi, Takuyo Aita and Tetsuya YomoChapter 7 Searching for de novo Totally Random Amino Acid Sequences (pages 155–174): Cristiano Chiarabelli, Cecilia Portela Pallares and Anna QuintarelliChapter 8 Synthetic Genetic Codes as the Basis of Synthetic Life (pages 175–199): J. Tze?Fei Wong and Hong XueChapter 9 Toward Safe Genetically Modified Organisms through the Chemical Diversification of Nucleic Acids (pages 201–226): Piet Herdewijn and Philippe MarliereChapter 10 The Minimal Ribosome (pages 227–245): Hiroshi Yamamoto, Markus Pech, Daniela Wittek, Isabella Moll and Knud H. NierhausChapter 11 Semi?Synthetic Minimal Living Cells (pages 247–286): Pasquale Stano, Francesca Ferri and Pier Luigi LuisiChapter 12 Replicators: Components for Systems Chemistry (pages 287–319): Olga Taran and Gunter von KiedrowskiChapter 13 Dealing with the Outer Reaches of Synthetic Biology Biosafety, Biosecurity, IPR, and Ethical Challenges of Chemical Synthetic Biology (pages 321–342): Markus Schmidt, Malcolm Dando and Anna DeplazesChapter 14 The Synthetic Approach in Biology: Epistemological Notes for Synthetic Biology (pages 343–362): Pier Luigi Luisi