دانلود کتاب Ciba Foundation Symposium 60 - Molecular Interactions and Activity in Proteins

Content: Chapter 1 Intramolecular Interactions, Enzyme Activity and Models (pages 1–22): William N. LipscombChapter 2 Solvents, Interfaces and Protein Structure (pages 23–45): F.M. Richards and T. RichmondChapter 3 The Chemical Properties of Out?of?Equilibrium States of Proteins and the Role of these States in Protein Functioning (pages 47–54): L.A. BlumenfeldChapter 4 Flexibility and Rigidity in Protein Crystals (pages 55–61): D.M. BlowChapter 5 Coenzyme?Induced Conformational Changes and Substrate Binding in Liver Alcohol Dehydrogenase (pages 63–80): Carl?Ivar Branden and Hans EklundChapter 6 The Consequences of Nucleotide Binding to Liver Alcohol Dehydrogenase (pages 81–88): H. GutfreundChapter 7 Origins of Specificity in the Binding of Small Molecules to Dihydrofolate Reductase (pages 89–104): Gordon C.K. RobertsChapter 8 Polypeptide Hormone?Receptor Interactions: The Structure and Receptor Binding of Insulin and Glucagon (pages 105–121): S. Bedarkar, T.L. Blundell, S. Dockerill, I.J. Tickle and S.P. WoodChapter 9 Perturbations of Model Protein Systems as a Basis for the Central and Peripheral Mechanisms of General Anaesthesia (pages 123–136): M.J. Halsey, F.F. Brown and R.E. RichardsChapter 10 Physical and Chemical Properties of Lysozyme (pages 137–185): C.C.F. Blake, D.E.P. Grace, L.N. Johnson, S.J. Perkins, D.C. Phillips, R. Cassels, C.M. Dobson, F.M. Poulsen and R.J.P. WilliamsChapter 11 The Free Radical in Ribonucleotide Reductase from E. coli (pages 187–196): Britt?Marie Sjoberg and Astrid GraslundChapter 12 Dynamics of Local Conformation and Enzyme Function (pages 197–223): Bert L. Vallee and James F. RiordanChapter 13 To Stabilize a Transition State … (pages 225–242): Joshua Boger and Jeremy R. KnowlesChapter 14 Stereochemical Studies of Enzymic C?Methylations (pages 243–268): D. ArigoniChapter 15 Concluding Remarks (pages 269–270):