جزییات کتاب
This new edition of the benchmark text on clinical pediatric endocrinology still remains at the forefront of world clinical opinion. Furthermore, the style, which has been the hallmark of the book for the last 20 years, has been maintained for this Fifth Edition.New features of this Fifth Edition include:Special new chapters cover the fetal origins of adult disease and the endocrine consequences and management of critical illnessNow opens with a basic science section summarizing the mechanisms of hormone action, genomics, proteomics and the application of molecular biology to clinical practiceTwo new co-editors have been introduced - Peter Clayton and Rosalind BrownEvery chapter has been updatedContent: Chapter 1 Principles of Hormone Action (pages 1–17): Melissa WestwoodChapter 2 Genetics, Genomics, Proteomics, and Bioinformatics (pages 18–44): Peter KoppChapter 3 Measuring Hormones, Molecular Tests, and Their Clinical Application (pages 45–66): Jan M. Wit and Marcel KarperienChapter 4 Congenital Disorders of the Hypothalamic?Pituitary Axis (pages 67–89): Ameeta Mehta and Mehul T. DattaniChapter 5 Normal and Disordered Growth (pages 90–112): Leena Patel and Peter E. ClaytonChapter 6 Genetic Syndromes and Dysmorphology (pages 113–123): Jennifer BatchChapter 7 Acquired Abnormalities of the Hypothalamic?Pituitary Axis Leading to Growth Impairment (pages 124–152): Dennis J. Brenner and Edward O. ReiterChapter 8 Development of the Reproductive Systems (pages 153–170): John C. AchermannChapter 9 Ambiguous Genitalia (pages 171–182): Ieuan A. HughesChapter 10 Normal and Abnormal Puberty (pages 183–210): Mehul T. Dattani and Peter C. HindmarshChapter 11 Gynecology (pages 211–217): Sarah M. CreightonChapter 12 The Thyroid and its Disorders (pages 218–253): Rosalind S. Brown and Stephen HuangChapter 13 The Parathyroid and Disorders of Calcium Metabolism (pages 254–279): Jeremy AllgroveChapter 14 Disorders of Bone Metabolism (pages 280–292): Ingrid A. HolmChapter 15 The Adrenal Cortex and its Disorders (pages 293–351): Walter L. MillerChapter 16 Polyglandular Syndromes (pages 352–366): Catherine J. Owen, Tim D. Cheetham and Simon H.S. PearceChapter 17 Disorders of Water Balance (pages 367–395): Rebecca P. Green, Joseph A. Majzoub and Louis J. MugliaChapter 18 Endocrine Programming and the Fetal and Early?Life Origins of Adult Disease (pages 396–409): Caroline H.D. FallChapter 19 Weight Regulation and Monogenic Obesity (pages 410–418): I. Sadaf FarooqiChapter 20 Metabolic Consequences of Obesity and Their Management (pages 419–435): Michael FreemarkChapter 21 Diabetes Mellitus (pages 436–473): Andrew W. Norris and Joseph I. WolfsdorfChapter 22 Hypoglycemia (pages 474–491): Khalid Hussain and Mark J. DunneChapter 23 Endocrine Consequences of Systemic Disease: Critical Illness (pages 492–504): Greet Van Den BergheChapter 24 Consequences of Radiotherapy, Chemotherapy, and Bone Marrow Transplant (pages 505–522): Helena A. DaviesChapter 25 Tests and Normal Values in Pediatric Endocrinology (pages 523–564): Lesley J. Tetlow and Peter E. Clayton