دانلود کتاب Ciba Foundation Symposium - High Altitude Physiology: Cardiac and Respiratory Aspects

Volume 1 Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs successfully upholds the goals of the Wiley Encyclopedia of Clinical Trials by combining both previously-published and newly developed contributions written by over 100 leading academics, researchers, and practitioners in a comprehensive, approachable format. The result is a succinct reference that unveils modern, cutting-edge approaches to acquiring and understanding data throughout the various stages of clinical trial design and analysis. Volume 2Featuring newly-written material as well as established literature from the Wiley Encyclopedia of Clinical Trials, this book provides a timely and authoritative review of techniques for planning clinical trials as well as the necessary inferential methods for analyzing collected data. This comprehensive volume features established and newly-written literature on the key statistical principles and concepts for designing modern-day clinical trials, such as hazard ratio, flexible designs, confounding, covariates, missing data, and longitudinal data. Examples of ongoing, cutting-edge clinical trials from today's research such as early cancer & heart disease, mother to child human immunodeficiency virus transmission, women's health initiative dietary, and AIDS clinical trials are also explored. Content: Chapter 1 Chairman's Introduction (page 1): P. Hugh?JonesChapter 2 The Influence of High Altitude on Physiology (pages 3–13): Alberto HurtadoChapter 3 Morphometric Evaluation of Changes in Lung Structure Due to High Altitude (pages 15–30): P.H. Burri and E. R. WeibelChapter 4 Chronic Mountain Sickness: Pathology and Definition (pages 31–40): J. Arias?StellaChapter 5 Cor Pulmonale in Chronic Mountain Sickness: Present Concept of Monge's Disease (pages 41–60): D. Penaloza, F. Sime and L. RuizChapter 6 Transarterial Leakage: A Possible Mechanism of High Altitude Pulmonary Oedema (pages 61–77): J.W. SeveringhausChapter 7 The Carotid Body in Animals at High Altitude (pages 79–88): C.W. EdwardsChapter 8 Suprapontine Influences on Hypoxic Ventilatory Control (pages 89–102): S.M. Tenney, P. Scotto, L.C. Ou, D. Bartlett, and J.E. RemmersChapter 9 Genetic Aspects of the Blunted Chemoreflex Ventilatory Response to Hypoxia in High Altitude Adaptation (pages 103–124): S. LahiriChapter 10 Some Observations on the Biochemistry of the Myocardium at High Altitude (pages 125–129): P. HarrisChapter 11 Coronary Blood Flow and Myocardial Metabolism in Man at High Altitude (pages 131–148): P.R. MoretChapter 12 Anatomy of the Coronary Circulation at High Altitude (pages 149–157): J. Arias?Stelalnad and M. TopilskyChapter 13 Resistance and Capacitance Vessels of the Skin in Permanent and Temporary Residents at High Altitude (pages 159–185): J. Durand and J.P. MartineaudChapter 14 Chairman's Closing Remarks (pages 187–188): P. Hugh?Jones