جزییات کتاب
Volume 1 Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs successfully upholds the goals of the Wiley Encyclopedia of Clinical Trials by combining both previously-published and newly developed contributions written by over 100 leading academics, researchers, and practitioners in a comprehensive, approachable format. The result is a succinct reference that unveils modern, cutting-edge approaches to acquiring and understanding data throughout the various stages of clinical trial design and analysis. Volume 2Featuring newly-written material as well as established literature from the Wiley Encyclopedia of Clinical Trials, this book provides a timely and authoritative review of techniques for planning clinical trials as well as the necessary inferential methods for analyzing collected data. This comprehensive volume features established and newly-written literature on the key statistical principles and concepts for designing modern-day clinical trials, such as hazard ratio, flexible designs, confounding, covariates, missing data, and longitudinal data. Examples of ongoing, cutting-edge clinical trials from today's research such as early cancer & heart disease, mother to child human immunodeficiency virus transmission, women's health initiative dietary, and AIDS clinical trials are also explored. Content: Chapter 1 Chairman's Opening Remarks (page 1): J. G. DanielliChapter 2 Actuarial Aspects of Human Lifespans (pages 2–20): B. BenjaminChapter 3 Parental Age Effects on Man (pages 21–34): Eeva JalavistoChapter 4 Studies on the Longevity and Mortality of English Thoroughbred Horses (pages 35–56): A. ComfortChapter 5 Lifespan of Cattle and Horses Under Various Climatic Conditions and the Reasons for Premature Culling (pages 57–71): W. HartwigChapter 6 Onset of Disease and the Longevity of Rat and Man (pages 72–89): Henry S. Simms, Benjamin N. Berg and Dean F. DaviesChapter 7 Lifespans of Mammalian and Bird Populations in Nature (pages 90–105): F. BourliereChapter 8 Arteriosclerosis in Birds (pages 106–114): S. ScheideggerChapter 9 Relation of Lifespan to Brain Weight and Body Weight in Mammals (pages 115–141): George A. SacherChapter 10 A Review of the Lifespans and Mortality Rates of Fish in Nature, and Their Relation to Growth and Other Physiological Characteristics (pages 142–180): R. J. H. Beverton and S. J. HoltChapter 11 Physiological Changes Accompanying Ageing in Fishes (pages 181–211): Shelby D. GerkingChapter 12 Longevity of Fishes in Captivity, with Special Reference to Those Kept in the New York Aquarium (pages 212–230): Ross F. NigkelliChapter 13 Factors Influencing the Lifespan of Bees (pages 231–246): Anna MaurizioChapter 14 The Biology of Ageing in Insects (pages 247–268): Morris RocksteinChapter 15 The Rate of Ageing in Drosophila Subobscura (pages 269–301): J. Maynard Smith