جزییات کتاب
This book brings together contributions from key investigators in the area of pathological pain. It covers the molecular basis of receptors and channels involved in nociception, the possible messages that cause neuropathic plasticity, spinal plasticity in neuropathy, plastic changes in opioid systems in neuropathy and opioid tolerance, and plastic changes related to pathological pain. Content: Chapter 1 Chair's Introduction (pages 1–3): Takao KumazawaChapter 2 Regulation Mechanisms of Vanilloid Receptors (pages 4–18): Makoto Tominaga, Mitsuko Numazaki, Tohko Iida, Tomoko Moriyama, Kazuya Togashi, Tomohiro Higashi, Namie Murayama and Tomoko TominagaChapter 3 Sodium Channels and Neuropathic Pain (pages 19–31): Jin Mo Chung and Kyungsoon ChungChapter 4 Ion Channel Activities Implicated in Pathological Pain (pages 32–46): John N. Wood, Bjarke Abrahamsen, Mark D. Baker, James D. Boorman, Emmanuelle Donier, Liam J. Drew, Mohammed A. Nassar, Kenji Okuse, Anjan Seereeram, Caroline L. Stirling and Jing ZhaoChapter 5 General Discussion I (pages 47–54): Chapter 6 Chronic Pain and Microglia: The Role of ATP (pages 55–67): Kazuhide Inoue, Makoto Tsuda and Schuichi KoizumiChapter 7 Neurotrophic Influences on Neuropathic Pain (pages 68–102): Stephen B. McMahon and William B. J. CaffertyChapter 8 Changes in DRG Neurons and Spinal Excitability in Neuropathy (pages 103–115): Koichi Noguchi, Koichi Obata and Yi DaiChapter 9 Functional Reorganization of the Spinal Pain Pathways in Developmental and Pathological Conditions (pages 116–131): M. Yoshimura, H. Furue, T. Nakatsuka, T. Matayoshi and T. KatafuchiChapter 10 Central Plasticity in Pathological Pain (pages 132–148): Min ZhuoChapter 11 General Discussion II (pages 149–154): Chapter 12 Anti?Opioid Systems in Morphine Tolerance and Addiction—Locus?Specific Involvement of Nociceptin and the NMDA Receptor (pages 155–166): Hiroshi UedaChapter 13 Chronic Morphine?Induced Plasticity among Signalling Molecules (pages 167–180): Alan R. Gintzler and Sumita ChakrabartiChapter 14 Opioid Tolerance and Neuroplasticity (pages 181–190): Jianren MaoChapter 15 General Discussion III (pages 191–193): Chapter 16 A Mechanism?Based Understanding of Bone Cancer Pain (pages 194–219): Patrick W. MantyhChapter 17 Mechanistic and Clinical Aspects of Complex Regional Pain Syndrome (CRPS) (pages 220–238): Ralf BaronChapter 18 Cortical Pathophysiology of Chronic Pain (pages 239–255): A. Vania ApkarianChapter 19 Final Discussion (pages 256–261):