دانلود کتاب Engineering the Genetic Code: Expanding the Amino Acid Repertoire for the Design of Novel Proteins

The ability to introduce non-canonical amino acids in vivo has greatly expanded the repertoire of accessible proteins for basic research and biotechnological application. Here, the different methods and strategies to incorporate new or modified amino acids are explained in detail, including a lot of practical advice for first-time users of this powerful technique. Novel applications in protein biochemistry, genomics, biotechnology and biomedicine made possible by the expansion of the genetic code are discussed and numerous examples are given. Essential reading for all molecular life scientists who want to stay ahead in their research.Content: Chapter 1 Introduction (pages 1–12): Chapter 2 A Brief History of an Expanded Amino Acid Repertoire (pages 13–30): Chapter 3 Basic Features of the Cellular Translation Apparatus (pages 31–65): Chapter 4 Amino Acids and Codons – Code Organization and Protein Structure (pages 66–89): Chapter 5 Reprograming the Cellular Translation Machinery (pages 90–183): Chapter 6 Implications and Insights: From Reprogrammed Translation and Code Evolution to Artificial Life (pages 184–212): Chapter 7 Some Practical Potentials of Reprogrammed Cellular Translation (pages 213–260):