دانلود کتاب Ciba Foundation Symposium 48 - Purine and Pyrimidine Metabolism

Content: Chapter 1 Chairman's Opening Remarks (pages 1–2): R. W. E. WattsChapter 2 Purine and Pyrimidine Metabolism: Pathways, Pitfalls and Perturbations (pages 3–21): J. Frank Henderson, Jeffrey K. Lowe and Jerzy BarankiewiczChapter 3 Microbial Models and Regulatory Elements in the Control of Purine Metabolism (pages 23–41): Josepha S. Gots, Charles E. Benson, Bjarne Jochimsen and K. R. KoduriChapter 4 Molecular Nature of Enzyme Regulation in Purine Biosynthesis (pages 43–64): James B. Wyngaarden and Edward W. HolmesChapter 5 Genetic Heterogeneity at the Locus for Hypoxanthine?Guanine Phosphoribosyltransferase (pages 65–81): William L. NyhanChapter 6 Factors in the Pathogenesis of the Brain Damage and Anaemia in the Lesch?Nyhan Syndrome (pages 83–96): R.O. MckeranChapter 7 Hypoxanthine?Guanine Phosphoribosyltransferase Activity in Individual Erythrocytes: Autoradiographic Studies in Heter Ozygotes (pages 97–104): B. T. Emmerson, R. B. Gordon and L. A. JohnsonChapter 8 Purine Biosynthesis in Mutant Mammalian Cells (pages 105–126): Gabrielle H. ReemChapter 9 Purine and Pyrimidine Nucleotides in Some Mutant Human Lymphoblasts (pages 127–142): G. Nuki, K. Astrini, D. Brenton, M. Cruikshank, J. Lever and J. E. SeegmillerChapter 10 Superactivity of Phosphoribosylpyrophosphate Synthetase, due to Feedback Resistance, Causing Purine Overproduction and Gout (pages 143–164): Oded Sperling, Pnina Boer, Sara Brosh, Esther Zoref and Andre de VriesChapter 11 Dietary Feedback Regulation of Purine and Pyrimidine Biosynthesis in Man (pages 165–178): N. Zollner and W. GrobnerChapter 12 Implications of Disorders of Purine Metabolism for the Kidney and the Urinary Tract (pages 179–206): Andre de Vries and Oded SperlingChapter 13 The Role of de novo Purine Synthesis in Lymphocyte Transformation (pages 207–224): A. C. Allison, T. Hovi, R. W. E. Watts and A. D. B. WebsterChapter 14 Purine Metabolism and Control of Cell Proliferation (pages 225–248): Tapani Hovi, Tapani Hovi, Anthony C. Allison, Kari O. Raivio and Antti VaheriChapter 15 The Effect of Adenosine on Lymphoid Cell Proliferation and Antibody Formation (pages 249–276): J. Edwin Seegmiller, T. Watanabe and Max H. SchreierChapter 16 Characterization of Human Adenosine Deaminase (pages 277–293): William N. Kelley, Peter E. Daddona and Martin B. van der WeydenChapter 17 The Purinergic Nerve Hypothesis (pages 295–314): Geoffrey BurnstockChapter 18 Inherited Metabolic Disease: Prospects for the Future in Both Basic and Clinical Research (pages 315–355): R. W. E. Watts