جزییات کتاب
This timely and most comprehensive reference available on the topic covers all the different aspects vital in the fight against the global obesity epidemic. Following a look at adipose tissue development and morphology, the authors go on to examine its metabolic and endocrine functions and its role in disease. The final section deals with comparative and evolutionary aspects of the tissue. The result is an essential resource for cell and molecular biologists, physiologists, biochemists, pharmacologists, and those working in the pharmaceutical industry.Content: Chapter 1 Transcriptional Control of Adipogenesis and Fat Cell Gene Expression (pages 1–20): Ursula A. White and Jacqueline M. StephensChapter 2 Cellular and Molecular Basis of Functional Differences among Fat Depots (pages 21–47): Thomas Thomou, Tamara Tchkonia and James L. KirklandChapter 3 Plasticity of the Adipose Organ (pages 49–67): Saverio CintiChapter 4 Biology of Adipose Tissue Stem Cells (pages 69–80): Jeffrey M. Gimble, Bruce A. Bunnell and Farshid GuilakChapter 5 Molecular Mechanisms of Adipocyte Lipolysis (pages 81–96): James G. Granneman and Hsiao?Ping H. MooreChapter 6 New Developments in the Lipolytic Processing of Triglyceride?Rich Lipoproteins (pages 97–108): Andre Bensadoun, Anne P. Beigneux, Loren G. Fong and Stephen G. YoungChapter 7 Intracellular Fatty Acid Transport, Activation, and Trafficking (pages 109–127): Doug MashekChapter 8 Aquaporins and Adipose Tissue: Lesson from Discovery to Physiopathology and to the Clinic of Aquaporin Adipose (AQP7) (pages 129–147): Ken KishidaChapter 9 Signaling Pathways Controlling Lipolysis and Lipid Mobilization in Humans (pages 149–179): Max LafontanChapter 10 Leptin Secretion and Action (pages 181–199): Robert V. ConsidineChapter 11 Adiponectin (pages 201–230): Jonathan P. Whitehead and Ayanthi A. RichardsChapter 12 Preadipocyte Factor?1 and Adipose Tissue?Specific Secretory Factor/Resistin – Two Secreted Factors from Adipose Tissue: Role in Adipogenesis and Insulin Resistance (pages 231–243): Hei Sook Sul, Yuhui Wang and Carolyn HudakChapter 13 Adipose Tissue and Blood Pressure Regulation (pages 245–263): Lisa A. Cassis and Sara B. PoliceChapter 14 Adipokines, Inflammation, and Obesity (pages 265–281): Karine ClementChapter 15 Depot?Specific Biology of Adipose Tissues: Links to Fat Distribution and Metabolic Risk (pages 283–306): Mi?Jeong Lee and Susan K. FriedChapter 16 Viral Induction of Obesity and Adipogenesis (pages 307–332): Magdalena Pasarica, Rohan N. Dhurandhar, Nazar Mashtalir and Nikhil V. DhurandharChapter 17 Adipose Tissue Cachexia (pages 333–345): Michael John TisdaleChapter 18 Obesity and Diabetes: Lipotoxicity (pages 347–368): Christopher J. Lelliott, Matej Oresic and Antonio J. Vidal?PuigChapter 19 Obesity and Cancer (pages 369–384): Andrew G. RenehanChapter 20 Overview of Acquired and Genetic Lipodystrophies (pages 385–402): Tisha Joy and Robert A. HegeleChapter 21 Mouse Models of Lipodystrophy (pages 403–422): Jimmy Donkor and Karen ReueChapter 22 Caloric Restriction, Longevity, and Adiposity (pages 423–439): Leanne M. Redman and Eric RavussinChapter 23 Peroxisome Proliferator?Activated Receptor??: A Key Regulator of Adipose Tissue Formation, Remodeling, and Metabolism (pages 441–458): Olga Astapova and Todd LeffChapter 24 Early?Life Programming of Adipogenesis and Adiposity (pages 459–472): Roselle L. Cripps and Susan E. OzanneChapter 25 Evolutionary Aspects of Obesity and Adipose Tissue Function (pages 473–490): Jonathan C. K. Wells