دانلود کتاب Molecular Hematology, Third Edition

Now in its third edition, Molecular Hematology has been thoroughly updated to incorporate recent advances in molecular research. The aim of the book remains the same – to provide a core knowledge base for those with little exposure to molecular biological techniques. Molecular biology has had a significant impact on the understanding of blood diseases and this book shows how molecular techniques can be used in diagnosis and treatment. In each chapter the authors summarize the impact made by molecular research on the understanding of the pathogenesis of the disorder featured, and highlight the molecular strategies that exist, or are being currently investigated, for therapeutic purposes. There are six brand new chapters in this edition: History and development of molecular biology Pharmacogenomics Anemia of chronic disease Molecular pathogenesis of malaria Molecular basis of transplantation Cancer stem cells Presented in an extremely readable style with clear two-color line diagrams, this book is designed for the non-specialist and will be an invaluable resource for all trainee hematologists.Content: Chapter 1 Beginnings: The Molecular Pathology of Hemoglobin (pages 1–18): David WeatherallChapter 2 Molecular Cytogenetics and Array?Based Genomic Analysis (pages 19–25): Debra M Lillington, Silvana Debernardi and Bryan D YoungChapter 3 Stem Cells (pages 26–41): Eyal C Attar and David T ScaddenChapter 4 The Genetics of Acute Myeloid Leukemias (pages 42–50): Carolyn J Owen and Jude FitzgibbonChapter 5 Secondary Myelodysplasia/Acute Myelogenous Leukemia: Assessment of Risk (pages 51–56): D Gary Gilliland and John G GribbenChapter 6 Detection of Minimal Residual Disease in Hematological Malignancies (pages 57–75): John G GribbenChapter 7 Chronic Myelogenous Leukemia (pages 76–88): Alfonso Quintas?Cardama, Jorge Cortes, Hagop Kantarjian and Susan O'BrienChapter 8 Myelodysplastic Syndromes (pages 89–103): M Mansour Ceesay, Wendy Ingram and Ghulam J MuftiChapter 9 Myeloproliferative Disorders (pages 104–116): Anthony J Bench, George S Vassiliou and Anthony R GreenChapter 10 Lymphoma Genetics (pages 117–126): Anthony G Letai and John G GribbenChapter 11 The Molecular Biology of Multiple Myeloma (pages 127–139): Wee Joo Chng and P Leif BergsagelChapter 12 The Molecular Basis of Anemia (pages 140–164): Lucio Luzzatto and Anastasios KaradimitrisChapter 13 Anemia of Chronic Disease (pages 165–168): Tomas GanzChapter 14 The Molecular Basis of Iron Metabolism (pages 169–178): Nancy C Andrews and Tomas GanzChapter 15 Hemoglobinopathies Due to Structural Mutations (pages 179–195): D Mark Layton and Ronald L NagelChapter 16 Molecular Pathogenesis of Malaria (pages 196–207): David J Roberts and Chetan E ChitnisChapter 17 Molecular Coagulation and Thrombophilia (pages 208–218): Bjorn Dahlback and Andreas HillarpChapter 18 The Molecular Basis of Hemophilia (pages 219–232): Paul Lf GiangrandeChapter 19 The Molecular Basis of Von Willebrand Disease (pages 233–245): Luciano Baronciani and Pier Mannuccio MannucciChapter 20 Platelet Disorders (pages 246–258): Kenneth J ClemetsonChapter 21 The Molecular Basis of Blood Cell Alloantigens (pages 259–275): Willem H Ouwehand and Cristina NavarreteChapter 22 Functions of Blood Group Antigens (pages 276–286): Jonathan S Stamler and Marilyn J TelenChapter 23 Autoimmune Hematological Disorders (pages 287–305): Drew Provan, Adrian C Newland and John W SempleChapter 24 Hematopoietic Growth Factors: A 40?year Journey from Crude “Activities” to Therapeutic Proteins (pages 306–317): Graham Molineux and Stephen J SzilvassyChapter 25 Molecular Therapeutics in Hematology: Gene Therapy (pages 318–335): Jeffrey A MedinChapter 26 Pharmacogenomics (pages 336–349): Leo Kager and William E EvansChapter 27 Gene Expression Profiling in the Study of Lymphoid Malignancies (pages 350–359): Ulf Klein and Riccardo Dalla?FaveraChapter 28 History and Development of Molecular Biology (pages 360–369): Paul MossChapter 29 Cancer Stem Cells (pages 370–379): David C Taussig and Dominique BonnetChapter 30 Molecular Basis of Transplantation (pages 380–389): Francesco Dazzi