دانلود کتاب Cholinergic Mechanisms: Function and Dysfunction

The cholinergic synapse is an important interdisciplinary research topic. In the first place, it stands as a useful system for investigating many fundamental issues of development, structure and function/malfunction of synapses in general. Also, its crucial biological role makes it the target of a variety of natural toxins and synthetic poisons and drugs. For example, it is the target of the first generation of anti-Alzheimer drugs, of nerve agents and insecticides, of botulinum toxin and the South American Indian arrow poison, curare, and of drugs for the treatment of myasthenia gravis and glaucoma. It is therefore not surprising to find many neuroscientists, with a broad range of interests, focusing their research on this synapse. The triennnial symposium on cholinergic mechanisms provides a key multidisciplinary forum for their interaction, and the proceedings, compiled in this volume, of the Eleventh ISCM, held in St. Moritz in May 2002, provide a cutting edge profile of research progress in this important field of study.