دانلود کتاب Ciba Foundation Symposium 94 - Malaria and the Red Cell

Volume 1 Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs successfully upholds the goals of the Wiley Encyclopedia of Clinical Trials by combining both previously-published and newly developed contributions written by over 100 leading academics, researchers, and practitioners in a comprehensive, approachable format. The result is a succinct reference that unveils modern, cutting-edge approaches to acquiring and understanding data throughout the various stages of clinical trial design and analysis. Volume 2Featuring newly-written material as well as established literature from the Wiley Encyclopedia of Clinical Trials, this book provides a timely and authoritative review of techniques for planning clinical trials as well as the necessary inferential methods for analyzing collected data. This comprehensive volume features established and newly-written literature on the key statistical principles and concepts for designing modern-day clinical trials, such as hazard ratio, flexible designs, confounding, covariates, missing data, and longitudinal data. Examples of ongoing, cutting-edge clinical trials from today's research such as early cancer & heart disease, mother to child human immunodeficiency virus transmission, women's health initiative dietary, and AIDS clinical trials are also explored. Content: Chapter 1 Introduction (pages 1–2): D.J. WeatherallChapter 2 Erythrocyte Membrane Structure and Function (pages 3–23): M. J. A. TannerChapter 3 Maturation of the Intracellular Parasite and Antigenicity (pages 24–44): K. N. Brown, D. B. Boyle and C. I. NewboldChapter 4 Structural Alteration of the Erythrocyte Membrane During Malarial Parasite Invasion and Intraerythrocytic Development (pages 45–63): Masamichi Aikawa and Louis H. MillerChapter 5 Transport of Ions in Erythrocytes Infected by Plasmodia (pages 64–73): Kazuyuki Tanabe, Ross B. Mikkelsen and Donald F. H. WallachChapter 6 The Anaemia of Plasmodium falciparum Malaria (pages 74–97): D. J. Weatherall, S. Abdalla and M. J. PippardChapter 7 The Spleen in Malaria (pages 98–116): David J. WylerChapter 8 Influence of the Spleen on the Expression of Surface Antigens on Parasitized Erythrocytes (pages 117–136): John W. Barnwell, Russell J. Howard and Louis H. MillerChapter 9 Protective Immunity to Malaria and Anti?Erythrocyte Autoimmunity (pages 137–158): W. JarraChapter 10 Genetic Variation in the Host and Adaptive Phenomena in Plasmodium falciparum Infection (pages 159–173): L. Luzzatto, F, O. Sodeinde and G. MartinitChapter 11 Glycophorins and Red Cell Invasion by Plasmodium falciparum (pages 174–195): Geoffrey Pasvol and Michele JungeryChapter 12 Expression of Inherited Resistance to Malaria in Culture (pages 196–205): Milton J. FriedmanChapter 13 Metabolism and Surface Transport of Parasitized Erythrocytes in Malaria (pages 206–221): Irwin W. ShermanChapter 14 Mode of Action of Antimalarial Drugs (pages 221–245): Coy D. FitchChapter 15 Closing Remarks (pages 246–247): D.J. Weatherall