دانلود کتاب Uremic Toxins

Reviews all the latest basic and clinical research findingsWith contributions from leading international experts in the field, this book is dedicated to all facets of uremic toxins research, including low molecular weight solutes, protein-bound solutes, and middle molecules. Moreover, it covers everything from basic mass spectrometry research to the latest clinical findings and practices.Uremic Toxins is divided into three sections:Section One, Uremic Toxins, explores the definition, classification, listing, and mass spectrometric analysis of uremic toxinsSection Two, Selected Uremic Toxins, describes key uremic toxins, explaining chemical structures, metabolism, analytical methods, plasma levels, toxicity, clinical implications, and removal methods. Among the uremic toxins covered are indoxyl sulfate, asymmetric dimethylarginine, PTH, ?2-microglobulin, and AGEsSection Three, Therapeutic Removal of Uremic Toxins, describes how uremic toxins can be removed by hemodialysis, peritoneal dialysis, and oral sorbentAll chapters are based on the authors' thorough review of the literature as well as their own personal laboratory and clinical experience. References at the end of each chapter provide a gateway to the literature in the field.Reviewing all the latest basic and clinical research findings, Uremic Toxins will help bench scientists in nephrology advance their own investigations. It will also help clinicians take advantage of the latest tested and proven treatments for the management of chronic kidney disease.Content: Chapter 1 Uremic Toxins: An Integrated Overview of Definition and Classification (pages 1–12): Richard J. Glassock and Shaul G. MassryChapter 2 Classification and a List of Uremic Toxins (pages 13–33): Nathalie Neirynck, Rita de Smet, Eva Schepers, Raymond Vanholder and Griet GlorieuxChapter 3 Analysis of Uremic Toxins with Mass Spectrometry (pages 35–50): Toshimitsu NiwaChapter 4 Indoxyl Sulfate (pages 51–76): Toshimitsu NiwaChapter 5 p?Cresyl Sulfate (pages 77–86): Anneleen Pletinck, Raymond Vanholder and Griet GlorieuxChapter 6 3?Carboxy?4?Methyl?5?Propyl?2?Furanpropionic Acid (pages 87–98): Toshimitsu NiwaChapter 7 Phenylacetic Acid (pages 99–107): Anna Schulz and Joachim JankowskiChapter 8 Homocysteine and Hydrogen Sulfide, Two Opposing Aspects in the Pathobiology of Sulfur Compounds in Chronic Renal Failure (pages 109–123): Alessandra F. Perna and Diego IngrossoChapter 9 Guanidino Compounds (pages 125–142): Sunny Eloot, Griet Glorieux, Peter Paul de Deyn and Raymond VanholderChapter 10 Asymmetric Dimethylarginine (pages 143–161): Vladimir Teplan and Jaroslav RacekChapter 11 Nicotinamide Metabolites (pages 163–175): Boleslaw Rutkowski and Przemyslaw RutkowskiChapter 12 Dicarbonyls (Glyoxal, Methylglyoxal, and 3?Deoxyglucosone) (pages 177–192): Naila Rabbani and Paul J. ThornalleyChapter 13 Glucose Degradation Products in Peritoneal Dialysis (pages 193–207): Monika Pischetsrieder and Sabrina GensbergerChapter 14 Dinucleoside Polyphosphates (pages 209–225): Joachim Jankowski and Vera JankowskiChapter 15 Parathyroid Hormone (pages 227–248): Shaul G. Massry and Miroslaw SmogorzewskiChapter 16 ?2?Microglobulin (pages 249–258): Suguru Yamamoto, Junichiro James Kazama, Hiroki Maruyama, Ichiei Narita and Fumitake GejyoChapter 17 Cytokines (pages 259–277): Bjorn Anderstam, Bengt Lindholm and Peter StenvinkelChapter 18 Free Immunoglobulin Light Chains (pages 279–291): Gerald Cohen and Walter H. HorlChapter 19 Advanced Glycation Endproducts (AGEs) (pages 293–304): Naila Rabbani and Paul J. ThornalleyChapter 20 Oxidized Albumin (pages 305–314): Maurizio Bruschi, Giovanni Candiano, Laura Santucci and Gian Marco GhiggeriChapter 21 Therapeutic Removal of Uremic Toxins by Hemodialysis (pages 315–330): Tammy L. Sirich, Pavel Aronov and Timothy W. MeyerChapter 22 Therapeutic Removal of Uremic Toxins by Peritoneal Dialysis (pages 331–357): Malgorzata Debowska, Elvia Garcia?Lopez, Jacek Waniewski and Bengt LindholmChapter 23 Therapeutic Removal of Uremic Toxins by Oral Sorbent (pages 359–371): Toshimitsu Niwa