جزییات کتاب
Summarizing molecular aspects, diagnostic as well as therapeutic issues, this book is the very first and most comprehensive on hereditary aspects of tumor diseases. All the contributors have been made fellows of the Ingrid zu Solms Foundation due to their outstanding achievements in scientific research, and they discuss here the latest aspects in the diagnosis, disease management, and treatment of hereditary tumor diseases and syndromes. A must-have ready reference for medical and biology students, MDs, PhDs, physicians, and researchers. Content: Chapter 1 General Insights into Tumor Invasion, Progression, and Metastasis (pages 1–24): Prof. Dr. Heike AllgayerChapter 2 The Genetic Background of Hereditary Tumor Diseases (pages 25–39): Ortrud K. SteinleinChapter 3 Family Cancer Syndromes (pages 41–86): Prof. Dr. Helga RehderChapter 4 Genetic Dysmorphic Syndromes Leading to Tumorigenesis (pages 87–105): Gabriele Gillessen?KaesbachChapter 5 Hereditary Brain Tumors (pages 107–125): Christine MarosiChapter 6 Neurofibromatosis (pages 127–145): Katharina Wimmer, Hildegard Kehrer?Sawatzki and Eric LegiusChapter 7 Retinoblastoma: The Prototypic Hereditary Tumor (pages 147–162): Helen Dimaras and Brenda L. GallieChapter 8 Hereditary Cancer in the Head and Neck (pages 163–168): Barbara WollenbergChapter 9 Hereditary Medullary and Familial Non?Medullary Thyroid Carcinoma (pages 169–181): Theresia WeberChapter 10 Lung Tumors (pages 183–192): Sarah Danson, M Dawn Teare and Penella WollChapter 11 Hereditary Breast Cancer (pages 193–206): Rita Katharina SchmutzlerChapter 12 Hereditary Ovarian and Endometrial Cancer (pages 207–214): Marion KiechleChapter 13 Prostate Cancer (pages 215–229): Raphaela WaidelichChapter 14 Wilms and Rhabdoid Tumors of the Kidney (pages 231–243): Brigitte Royer?PokoraChapter 15 Hereditary Renal Tumors of the Adult (pages 245–256): Liesbeth Spruijt and Nicoline HoogerbruggeChapter 16 Gastrointestinal Polyposis Syndromes (pages 257–280): Waltraut Friedl and Stefanie VogtChapter 17 Lynch Syndrome (HNPCC) (pages 281–294): Gabriela MosleinChapter 18 Gastrointestinal Stromal Tumors (GISTs) (pages 295–307): Maria Debiec?RychterChapter 19 Hereditary Gastric Cancer (pages 309–343): Holger Vogelsang and Gisela KellerChapter 20 Pancreatic Cancer (pages 345–354): Nils Habbe and Babette SimonChapter 21 Liver Tumors (pages 355–376): Sabine J. PresserChapter 22 DNA?Repair Deficiency and Cancer: Lessons from Lymphoma (pages 377–391): Krystyna H. Chrzanowska, Martin Digweed, Karl Sperling and Eva SeemanovaChapter 23 Familial Leukemias (pages 393–410): Christa FonatschChapter 24 Malignant Melanoma (pages 411–420): Carola Berking and Anja Katrin BosserhoffChapter 25 Xeroderma Pigmentosum, Cockayne Syndrome, Trichothiodystrophy – Defects in DNA Repair and Carcinogenesis (pages 421–439): Steffen EmmertChapter 26 Hereditary Tumors in Children (pages 441–452): Prof. Dr. Simone FuldaChapter 27 Sarcomas and Bone Tumors in Adulthood (pages 453–466): Eva WardelmannChapter 28 Genetic Counseling for Hereditary Tumors (pages 467–485): Dorothea Gadzicki and Brigitte SchlegelbergerChapter 29 Psycho?Oncologic Aspects of Hereditary Tumors and Predictive Testing (pages 487–499): Mechthild NeisesChapter 30 Molecular Targeted Therapy (pages 501–514): Prof. Dr. Heike Allgayer and Prof. Dr. Simone Fulda