Content: Preface, Pages v-vi, Philippe GarriguesList of participants of European Projects, Pages xvii-xixAbbreviations, Pages xxi-xxiiChapter 1 - Induction of Molluscan Cytochrome P450 Monooxygenase System as a Biomarker of Organic Pollution in Environmental Monitoring, Pages 1-28, L.D. Peters, D.R. LivingstoneChapter 2 - Sensitivity and Specificity of Metallothionein as a Biomarker for Aquatic Environment Biomonitoring, Pages 29-43, A. Viarengo, B. Burlando, V. Evangelisti, S. Mozzone, F. DonderoChapter 3 - Genotoxicity Biomarkers in Aquatic Organisms as Indicators of Carcinogenic Marine Pollutants, Pages 45-64, C. Bolognesi, P. DeganChapter 4 - DNA Adduct Detection in Mussels Exposed to Bulky Aromatic Compounds in Laboratory and Field Conditions, Pages 65-83, P. VenierChapter 5 - Developmental, Cytogenetic and Biochemical Effects of Spiked or Environmentally Polluted Sediments in Sea Urchin Bioassays, Pages 85-129, G. Pagano, L.G. Korkina, M. Iaccarino, A. De Biase, I.B. Deeva, Y.K. Doronin, M. Guida, G. Melluso, S. Meriç, R. Oral, N.M. Trieff, M. WarnauChapter 6 - Comparative study of sediment and mussel aromatic compound content in European coastal environments. Relationship with specific biomarkers, Pages 131-177, P. Baumard, H. Budzinski, P. Garrigues, C. Raoux, J. Bellocq, S. ThompsonChapter 7 - Monitoring of Biological Effects of Pollutants: Field Application, Pages 179-213, T. Burgeot, G. Bocquené, E. His, F. Vincent, O. Geffard, R. Beiras, H. Goraguer, F. GalganiChapter 8 - Biochemical Markers in Mussel, Mytilus Sp., and Pollution Monitoring in European Coasts: Data Analysis, Pages 215-236, J.F. Narbonne, M. Daubèze, P. Baumard, H. Budzinski, C. Clérandeau, F. Akcha, P. Mora, P. GarriguesChapter 9 - Investigation of Genotoxicity and Immunotoxicity for Monitoring Marine Pollution in the Baltic Sea and Mediterranean Sea, Pages 237-257, H. Dizer, E. Unruh, V. Bissinger, P.-D. HansenChapter 10 - Biochemical Tools for the Assessment of Pesticide Exposure in a Deltaic Environment: The Use of Cholinesterases and Carboxylesterases, Pages 259-278, C. Porte, E. Escartín, V. BorghiChapter 11 - Environmental Monitoring in the North Sea by Combining Biomarker Studies in the Sea Star Asterias Rubens with Sediment Quality Assessment Based on Sea Urchin Bioassays, Pages 279-330, P.J. den Besten, J.F. Postma, S. de Valk, M. Dubbeldam, J.M. EveraartsChapter 12 - Cholinesterase Activity as a Bioindicator for Monitoring Marine Pollution in the Baltic Sea and the Mediterranean Sea, Pages 331-342, H. Dizer, H.C. da Silva de Assis, P.-D. HansenChapter 13 - Evaluation of Various Biomarkers in the Wild Fish Serranus Cabrilla Collected in the NW Mediterranean Sea, Pages 343-356, M. Roméo, X. Stien, M. Gnassia-Barelli, M. LafaurieChapter 14 - Microbiological Indicators for Monitoring Marine Pollution in the Baltic Sea and the Mediterranean Sea, Pages 357-366, H. Dizer, P.-D. HansenChapter 15 - Isolation of Cytochrome P450 CDNAS (CYP1A1 and CYP4T2) from the Sea Bass (Dicentrarchus Labrax): Tools for Biomonitoring Sea Pollution, Pages 367-392, C. Sabourault, X. Stien, J.B. Bergé, J.P. Girard, M. Lafaurie, M. AmichotChapter 16 - Inhibitory Effects of Heavy Metals on CYP1A1 Induction in Black Seabream (Spondyliosoma Cantharus) Hepatocyte Cultures, Pages 393-408, C. Risso de Faverney, G. de Sousa, M. Lafaurie, R. RahmaniChapter 17 - Biochemical Responses of Crabs (Carcinus spp) to Polycyclic Aromatic Hydrocarbons (PAHs) as the Basis for New Biomarker Assays, Pages 409-429, C.H. Walker, D. SavvaChapter 18 - Cloning of Metallothionein cDNAs in Carcinus Maenas, Pages 431-438, D. Savva, B. LiChapter 19 - Development of Cytochrome P450 Biomarkers from Posidonia Oceanica, Pages 439-446, Anne Schoendorf, Irène Benveniste, Jean-Pierre SalaünMeasurement of Total Cytochrome P450 Content in Digestive Gland Microsomes of Mussel (Mytilus sp.), Pages 449-450, D.R. Livingstone, L.D. PetersMeasurement of Cytochrome P450 Immunopositive Proteins in Digestive Gland Microsomes of Mussel (Mytilus sp.) by Western Analysis, Pages 451-452, L.D. Peters, D.R. LivingstoneMetallothionein Assay, Pages 453-454, A Viarengo, B. Burlando, V. Evangelisti, S. Mozzone, F. DonderoEvaluation of Lysosomal Membrane Stability, Pages 455-459, A Viarengo, B. Burlando, V. Evangelisti, S. Mozzone, F. DonderoAlkaline filter elution method, Pages 461-466, C. Bolognesi, P. DeganMussel Micronucleus test, Pages 467-469, C. Bolognesi, P. Degan32Detection of bulky aromatic DNA adducts by P-postlabelling, Pages 471-474, P. VenierEmbryotoxicity on sea urchins, Pages 475-476, G. Pagano, L.G. Korkina, M. Iaccarino, A. de Biase, I.B. Deeva, Y.K. Doronin, M. Guida, G. Melluso, R. Oral, N.M. Trieff, M. WarnauSediment spiking technique, Page 477, G. Pagano, L.G. Korkina, M. Iaccarino, A. de Biase, I.B. Deeva, Y.K. Doronin, M. Guida, G. Melluso, R. Oral, N.M. Trieff, M. WarnauMeasurement of oxidative activity: Luminol-dependent chemiluminescence and 8-oxodesoxyguanine, Pages 478-479, G. Pagano, L.G. Korkina, M. Iaccarino, A. de Biase, I.B. Deeva, Y.K. Doronin, M. Guida, G. Melluso, R. Oral, N.M. Trieff, M. WarnauChemical Analyses of PAH in Sediment and Mussels, Pages 481-486, P. Baumard, H. Budzinski, P. Garrigues, C. Raoux, J. Bellocq, S. ThompsonProcedures for Cholinesterase Determination in Fish and Mussel, Pages 487-489, T. Burgeot, G. Bocquené, E. His, F. Vincent, O. Geffard, R. Beiras, F. Quiniou, H. Goraguer, F. GalganiMicroplate Method for Measurement of EthoxyResorufin-O-Deethylase in Fish, Pages 491-494, T. Burgeot, G. Bocquené, E. His, F. Vincent, O. Geffard, R. Beiras, F. Quiniou, H. Goraguer, F. GalganiMytilus sp.Benzo(a)pyrene Hydroxylase Activity Measurement in Microsomes from, Pages 495-497, J.F. Narbonne, M. Daubèze, P. Baumard, H. Budzinski, C. Clérandeau, F. Akcha, P. Mora, P. GarriguesDetermination of Cholinesterase Activity in Mussel Gills, Pages 499-500, J.F. Narbonne, M. Daubèze, P. Baumard, H. Budzinski, C. Clérandeau, F. Akcha, P. Mora, P. GarriguesChemical analysis: PAHs, PCBs and Pesticides, Pages 501-502, C. Porte, D. BarceloBiochemical Markers Acetylcholinesterase Activity and Cytochrome P450, Pages 503-504, C. Porte, D. BarceloAsterias rubensMeasurement of DNA-Strandbreaks in Tissue of the Sea Star, Pages 505-507, P.J. den Besten, J.F. Postma, S. de Valk, M. Dubbeldam, J.M. EveraartsMeasurement of Sediment-Toxicity Using a Fertilization and Embryonic Development Assay with the Sea Urchins (Psammechinus miliaris, Paracentrotus lividus), Pages 509-512, P.J. Den Besten, J.F. Postma, S. De Valk, M. Dubbeldam, J.M. EveraatsDetermination of EROD, GST and AChE Activities in painted comber (Serranus cabrilla), Pages 513-516, M. Roméo, X. Stien, M. Gnassia-Barelli, M. LafaurieMiniaturized DNA Unwinding Assay Employing Hydroxyapatite “Batch” Elution, Pages 517-518, P. Hansen, H. DizerDicentrarchus labraxMolecular Cloning of CYP Genes in the Sea Bass (Dicentrarchus labrax): Experimental Procedures, Pages 519-525, C. Sabourault, X. Stien, J.B. Bergé, J.P. Girard, M. Lafaurie, M. AmichotFish Hepatocyte Cultures, Pages 527-528, C. Risso de Faverney, G. de Sousa, M. Lafaurie, R. RahmaniDetermination of Cytochromes P450 Expression and Induction in Black Seabream (Spondyliosama cantharus): Enzyme Activities, Northern and Western Blots, Pages 529-532, C. Risso de Faverney, G. de Sousa, M. Lafaurie, R. RahmaniCarcinusBiochemical Responses of Crabs ( spp) to Polycyclic Aromatic Hydrocarbons (PAHs) as the Basis for New Biomarkers Assays, Pages 533-536, C.H. Walker, D. SavvaCarcinus MaenasCloning of Metallothionein cDNAs in, Pages 537-538, D. Savva, B. LiPosidonia oceanicaDevelopment of Biomarkers from seagrass, Pages 539-541, A. Schoendorf, I. Benveniste, J.P. SalaünList of Contributors, Pages 543-548Index of Keywords, Pages 549-550